Amphotericin B. Amphotericin B has been the mainstay of antifungal therapy for invasive and serious mycoses, but other antifungals (eg, fluconazole, voriconazole, posaconazole, the echinocandins) are now considered first-line drugs for many of these infections. Ketoconazole. Ketoconazole (Nizoral™) is used to treat fungal infections where other treatments have failed or are contraindicated. It is effective for yeasts and dermatophytes and is usually prescribed in a daily dose of 200mg after food.

Oral antifungal drugs include fluconazole and itraconazole. These drugs can be used to treat more severe fungal infections. Terbinafine is an oral antifungal medicine that may be used to treat fungal infections of the nails.