Cold Chain Equipment is the lifeline for heat-sensitive vaccines and is essential for transportation of these vaccines from the place of manufacturing to the place of field storage and final carriage to the place of immunization. Thus, CFC-free cold chain equipment ensures a pre-determined safe temperature range (-3 to + 10 C) for a particular period known as cold life of the product.

The cold life period varies according to the product classifications made by WHO i.e for large equipment like cold boxes, the cold life is high whereas for small equipment like vaccine carriers the cold life requirement is less.