Isothiazolone off by algae and bacteria proteins into the key role in the killing. Isothiazolone in contact with the micro-organisms that can quickly and irreversibly inhibit its growth, resulting in the death of microbial cells, it is common for bacteria, fungi, algae, and so has a strong role in killing and suppression. Efficient killing, with no residue, safe operation, good compatibility, stability, use and low cost. With chlorine and the majority of anions and cations and nonionic surfactant with immiscibility. High-dose, isothiazolone biological sticky mud off a significant effect. Isothiazolone is a broad-spectrum, high efficiency, low toxicity, non-oxidizing biocide. Widely used in oil fields, paper, chemicals, cutting oil, leather, ink, dyes, and leather industries.